Analytical population
Data quality and cohort
Quality-control attrition, recovery-phase harmonization, and frozen cohort support.
Evidence scope
Scope, workflow status, and summary measures
Source InventoryCanonical Dataset ConstructionQuality ControlMetadata HarmonizationFrozen Controls Only Cohort
Source inventoryBuild source manifestComplete
CanonicalizationBuild canonical datasetComplete
Quality controlPaw aggregation and quality controlComplete
Metadata harmonizationHarmonize analysis metadataComplete
Frozen cohortBuild frozen controls-only cohortComplete
- Source-column entries across registered exports
- 1,069 column entries Source Inventory
- Distinct raw source labels (case-insensitive)
- 816 labels Source Inventory
- Distinct normalized source labels
- 764 labels Source Inventory
- Columns in the richest source export
- 332 columns Source Inventory
- Columns in the smallest source export
- 134 columns Source Inventory
- Source-column instances mapped to the canonical contract
- 528 column instances Source Inventory
- Source-column instances not carried forward
- 541 column instances Source Inventory
- Interlimb and phase-statistic instances not carried forward
- 260 column instances Source Inventory
- Secondary-statistic instances not carried forward
- 153 column instances Source Inventory
- Support and sequence instances not carried forward
- 53 column instances Source Inventory
- Other Statistics instances not carried forward
- 50 column instances Source Inventory
- Acquisition-setting instances not carried forward
- 20 column instances Source Inventory
- Miscellaneous software instances not carried forward
- 5 column instances Source Inventory
- Rows in canonicalized dataset
- 2,101 rows Canonical Dataset Construction
- Canonical analysis fields
- 110 columns Canonical Dataset Construction
- Canonical output columns including provenance
- 113 columns Canonical Dataset Construction
- Columns entering paw aggregation
- 113 columns Quality Control
- Columns after paw aggregation
- 65 columns Quality Control
- Paw-specific source columns aggregated
- 96 columns Quality Control
- Per-paw metric families
- 24 metrics Quality Control
- Rows entering quality control
- 2,101 rows Quality Control
- Rows retained after quality control
- 1,524 rows Quality Control
- Rows excluded by quality control
- 577 rows Quality Control
- Animals retained after quality control
- 387 animals Quality Control
- Harmonization lineage checks passed
- Yes Metadata Harmonization
- Eligible cohort rows
- 396 rows Frozen Controls Only Cohort
- Eligible cohort animals
- 115 animals Frozen Controls Only Cohort
- Eligible cohort experiments
- 5 experiments Frozen Controls Only Cohort
Aggregate estimate plot
Quality-control exclusion fractions
Quality Control missing_required_identifier0.000
outside_principal_experiments0.000
baseline_timepoint0.254
excessive_measurement_missingness0.020
Uncertainty: Point estimates are shown because this table does not supply matching lower and upper interval columns.
View plotted values in tabular form
| Estimate | Marker | Fraction |
|---|---|---|
| missing_required_identifier | ▲ | 0.000 |
| outside_principal_experiments | ■ | 0.000 |
| baseline_timepoint | ■ | 0.254 |
| excessive_measurement_missingness | ● | 0.020 |
Aggregate estimate plot
Frozen cohort support by experiment and phase
Frozen Controls Only Cohort BMDM · Early18.000
BMDM · Middle18.000
IL4 · Early71.000
IL4 · Late7.000
IL4 · Middle20.000
NK1 · Early33.000
SHH · Late88.000
SHH · Middle50.000
VEGF · Early53.000
VEGF · Late10.000
VEGF · Middle28.000
Uncertainty: Point estimates are shown because this table does not supply matching lower and upper interval columns.
View plotted values in tabular form
| Estimate | Marker | Rows |
|---|---|---|
| BMDM · Early | ● | 18.000 |
| BMDM · Middle | ✦ | 18.000 |
| IL4 · Early | ◆ | 71.000 |
| IL4 · Late | ✦ | 7.000 |
| IL4 · Middle | ■ | 20.000 |
| NK1 · Early | ✦ | 33.000 |
| SHH · Late | ● | 88.000 |
| SHH · Middle | ◆ | 50.000 |
| VEGF · Early | ▲ | 53.000 |
| VEGF · Late | ◆ | 10.000 |
| VEGF · Middle | ● | 28.000 |
Quality Control
Exclusion counts
Summary method: approved_rows
- Indexed rows
- 4
- Eligible rows
- 4
Showing 1–4 of 4 matching rows
Filters combine with AND. Empty and unreported values sort last.
| baseline_timepoint | Yes | 534 | 0.254 |
|---|---|---|---|
| excessive_measurement_missingness | Yes | 43 | 0.020 |
| missing_required_identifier | No | 0 | 0.000 |
| outside_principal_experiments | No | 0 | 0.000 |
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Metadata Harmonization
Recovery-phase mapping
Summary method: approved_rows
- Indexed rows
- 23
- Eligible rows
- 23
Showing 1–23 of 23 matching rows
Filters combine with AND. Empty and unreported values sort last.
| BMDM | 0 | — | Yes | No | No |
|---|---|---|---|---|---|
| BMDM | 7 | Early | No | No | Yes |
| BMDM | 14 | Middle | No | No | Yes |
| IL4 | 0 | — | Yes | No | No |
| IL4 | 1 | Early | No | No | Yes |
| IL4 | 3 | Early | No | No | Yes |
| IL4 | 7 | Early | No | No | Yes |
| IL4 | 14 | Middle | No | No | Yes |
| IL4 | 21 | Middle | No | No | Yes |
| IL4 | 28 | Late | No | No | Yes |
| NK1 | 0 | — | Yes | No | No |
| NK1 | 7 | Early | No | No | Yes |
| SHH | 0 | — | Yes | No | No |
| SHH | 7 | Early | No | No | Yes |
| SHH | 14 | Middle | No | No | Yes |
| SHH | 21 | Middle | No | No | Yes |
| SHH | 28 | Late | No | No | Yes |
| SHH | 35 | Late | No | No | Yes |
| VEGF | 3 | Early | No | No | Yes |
| VEGF | 7 | Early | No | No | Yes |
| VEGF | 14 | Middle | No | No | Yes |
| VEGF | 21 | Middle | No | No | Yes |
| VEGF | 28 | Late | No | No | Yes |
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Metadata Harmonization
Recovery-phase support by experiment
Summary method: approved_rows
- Indexed rows
- 22
- Eligible rows
- 22
Showing 1–22 of 22 matching rows
Filters combine with AND. Empty and unreported values sort last.
| BMDM | 0 | 75 | 24 | 0 | 75 | 0 | 0 |
|---|---|---|---|---|---|---|---|
| BMDM | 7 | 74 | 24 | 74 | 0 | 0 | 74 |
| BMDM | 14 | 72 | 24 | 72 | 0 | 0 | 0 |
| IL4 | 0 | 133 | 132 | 0 | 133 | 0 | 0 |
| IL4 | 3 | 108 | 108 | 108 | 0 | 0 | 108 |
| IL4 | 7 | 70 | 70 | 70 | 0 | 0 | 70 |
| IL4 | 14 | 43 | 42 | 43 | 0 | 0 | 0 |
| IL4 | 21 | 19 | 19 | 19 | 0 | 0 | 0 |
| IL4 | 28 | 20 | 20 | 20 | 0 | 0 | 0 |
| NK1 | 0 | 98 | 30 | 0 | 98 | 0 | 0 |
| NK1 | 7 | 85 | 30 | 85 | 0 | 0 | 85 |
| SHH | 0 | 228 | 77 | 0 | 228 | 0 | 0 |
| SHH | 7 | 19 | 7 | 19 | 0 | 0 | 19 |
| SHH | 14 | 71 | 31 | 71 | 0 | 0 | 0 |
| SHH | 21 | 198 | 65 | 198 | 0 | 0 | 0 |
| SHH | 28 | 195 | 65 | 195 | 0 | 0 | 0 |
| SHH | 35 | 205 | 64 | 205 | 0 | 0 | 0 |
| VEGF | 3 | 110 | 106 | 110 | 0 | 0 | 110 |
| VEGF | 7 | 120 | 120 | 120 | 0 | 0 | 120 |
| VEGF | 14 | 79 | 79 | 79 | 0 | 0 | 0 |
| VEGF | 21 | 39 | 39 | 39 | 0 | 0 | 0 |
| VEGF | 28 | 40 | 39 | 40 | 0 | 0 | 0 |
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Frozen Controls Only Cohort
Selected-feature profiles by recovery phase
Summary method: animal_phase_mean_then_phase_median_iqr
- Indexed rows
- 9
- Eligible rows
- 396
Showing 1–9 of 9 matching rows
Filters combine with AND. Empty and unreported values sort last.
| fp_intensity_density | Early | 85.139 | 74.193 | 101.2 | 93 | 93 | 175 |
|---|---|---|---|---|---|---|---|
| fp_intensity_density | Middle | 78.048 | 63.932 | 90.206 | 58 | 58 | 116 |
| fp_intensity_density | Late | 62.625 | 52.741 | 66.940 | 33 | 33 | 105 |
| fp_intensity_loading_fraction | Early | 0.599 | 0.546 | 0.653 | 25 | 93 | 28 |
| fp_intensity_loading_fraction | Middle | 0.619 | 0.583 | 0.667 | 40 | 58 | 76 |
| fp_intensity_loading_fraction | Late | 0.597 | 0.566 | 0.623 | 22 | 33 | 74 |
| hp_loading_rate | Early | 3710.3 | 1273.2 | 4714.2 | 25 | 93 | 28 |
| hp_loading_rate | Middle | 614.4 | 306.5 | 1335.7 | 36 | 58 | 60 |
| hp_loading_rate | Late | 512.4 | 350.6 | 1002.2 | 22 | 33 | 74 |
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Frozen Controls Only Cohort
Experiment-by-phase support
Summary method: approved_rows
- Indexed rows
- 11
- Eligible rows
- 11
Showing 1–11 of 11 matching rows
Filters combine with AND. Empty and unreported values sort last.
| BMDM | Early | 18 | 6 |
|---|---|---|---|
| BMDM | Middle | 18 | 6 |
| IL4 | Early | 71 | 45 |
| IL4 | Late | 7 | 7 |
| IL4 | Middle | 20 | 16 |
| NK1 | Early | 33 | 12 |
| SHH | Late | 88 | 16 |
| SHH | Middle | 50 | 16 |
| VEGF | Early | 53 | 30 |
| VEGF | Late | 10 | 10 |
| VEGF | Middle | 28 | 20 |
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